The Sustainable Enterprises Network (RedES) drives changes towards sustainable production systems in companies and value chains in order to improve efficiency and competitiveness. Since 2013, RedES has been applied in Cundinamarca, Colombia through the RedES-CAR program. In this program, 550 companies have adopted the circular economy strategies of Cleaner Production and Industrial Symbiosis. These companies formulated 507 initiatives with total savings of $55,534 million COP.